How to Secrete A Substance More to Prevent Aging of Heart

According to a newest research published on New England Journal of Medicine, a specific substance prevented the aging of the heart and decreased the risk of death caused by heart failure.
 
The substance is a ketone body, which everybody can produce in the body.
 
How can a ketone body prevent the aging of the heart?
 
The number of heart beat in its lifetime is determined by a kind of animal.
 
The number is about 700 million times.
 
For example, the heart beat of a mouse is 600 times per minutes so that it reaches 70 million times in 2 years. That is why their lifespan is about 2 years.
 
The heart beat of a horse is about 45 times per minutes so that it reaches 70 million times in 25 years.
 
The less the number of heart beat is, the longer the lifespan is.
 
So it is important to decrease useless heart beat in order to prevent the aging of the heart, and the key factor is a ketone body.
 
But the amount of ketone bodies depends on a person.
 
Healthy person’s heart beat is about 100 thousand times per day. If it is less than 100 thousand times, their heart can keep healthy longer. The more the heart beat is exceeding 100 thousand times, the easier the heart is aging by the useless heart beat.
 
The more ketone bodies are, the faster the elevated heart beat comes back to the original state, reducing the burden on the heart and preventing the aging of the heart.
 
The more ketone bodies are, the more sufficiently heart beat goes down while sleeping, preventing the aging of the heart.
 
How to secrete more ketone bodies
 
Ketone bodies are produced in the liver and work as energy source to move the body instead of sugar and fat.
 
When you have shortness of breath after climbing up stairs, the heart starts to pump out blood to all the body to deliver oxygen in order to relieve shortness of breath.
 
When ketone bodies are used to pump out blood, the amount of blood pumped out at once increases because of the better energy efficiency, compared to normal energy sources such as carbohydrate or fat.
 
That means heart can work easily and suppresses heart beat, leading to long life of the heart.
 
How can we secrete more ketone bodies?
 
The most effective method is fasting.
 
A 46 years old male whose ketone bodies were 51 (μ mol/L) tried 2 days fasting with drinking a glass of vegetable juice for every meal. After 2 days fasting, his ketone bodies became 4665 (μ mol/L) which was more than 90 times.
 
The amount of ketone bodies produced in the body depends on the amount of sugar in the body. Sugar is used as the source of energy to move the body, but if the amount of sugar decreases due to fasting or other reasons, ketone bodies are produced in the liver as substitute energy of sugar.
 
But it is impossible to continue fasting long time.                                                                   
 
So how can we secrete more ketone bodies without trying too hard?
 
The important thing is making fasting time longer.
 
The recommended method is mini-fasting which keeps the interval between dinner and breakfast long.
 
A 50 year old woman whose ketone bodies were 19 (μ mol/L) (Reference value: 85 μ mol/L) attended an experiment. She was eating some snack after dinner so that the interval between the snack and breakfast was only 7 hours. She stopped eating snack and made the interval between dinner and breakfast 11 hours for 5 days. After the 5 days experiment, her ketone bodies were 497 (μ mol/L).