Lewy bodies are protein deposits built up in nerve cells of the brain, that is garbage accumulated in the nerve (Fig.1).
Lewy bodies can be accumulated in the nerves anywhere in the body. Lewy bodies tend to be accumulated in the temporal lobe of the brain, which creates meaning from what you see and hear.
When you see a person, the temporal lobe recognizes what you see as a person. But if Lewy bodies are accumulated in the temporal lobe, when you see a hanger, the temporal lobe can recognize it as a person.
This type of a disease is called Lewy body dementia (LBD). Lewy body dementia is the second most dementia after Alzheimer dementia.
Initial symptoms of Lewy body dementia are:
Visual hallucination (Fig. 2)
Shaking and rigidity (Fig. 3)
Inability to brush teeth, wear clothes, etc.
Changes of physical condition within a day such as sudden spacing-out (Fig. 4)
REM sleep behavior disorder is a sleep disorder in which people act out their dreams, involving abnormal behavior such as screaming, shouting, laughing, crying, arm flailing, kicking, punching, choking, and even jumping out of bed (Fig. 5).
The most obvious symptom is involuntary shaking of hands and feet. As the disease progresses, balance of the body is not good so that falling occurs easily. All the muscles become rigid, resulting in bedridden 10 years after development of the disease.
The cause is considered as that Lewy bodies are accumulated in the brain stem where controls the movement of the body (Fig. 6).
In recent years, it has turned out that combined application of medication and exercise improves the condition.