But the research about the bad substance has just started and there are a lot of unknown things.
The following information is based on the latest research.
The bad substance progressing aging is Osteopontin.
Osteopontin is a type of protein that is required to produce bones and kill bacteria from outside. But if osteopontin is secreted too much, inflammation of the whole body is caused.
In general, inflammation is like swelling of gams caused by toothache or sore throat caused by a common cold.
But the inflammation caused by osteopontin is as small as we can’t see, happens all the time in our body and progresses the aging of our body without cure.
In the body of centenarian, inflammation is not happening very much. That means the more there is inflammation in the body, the faster the aging can progress.
There are a lot of substances that cause inflammation, but it has turned out that osteopontin is something like a general manager of those substances.
What is the difference between people who have a lot of osteopontin and people who have less osteopontin?
People who have a lot of osteopontin have abnormality of Immune cells that kill external pathogen. The abnormality of immune cells causes the secretion of osteopontin, causing the inflammation everywhere in the body and progressing aging.
What makes immune cells abnormal?
That is visceral fat that is body fat that is stored around internal organs. The detailed mechanism is unknown yet, but the more visceral fat is, the more abnormal immune cells are.
Even if you lose weight and decrease visceral fat, osteopontin doesn’t decrease.
How can we prevent aging by decreasing osteopontin?
This is still under research but there are 3 things we need to pay attention to decrease osteopontin.
1. Oil: change oils from animal oil to oil rich in unsaturated fatty acid such as olive oil.
2. Stress: Try not to build up stress.
3. Intestinal bacteria: harmonize the balance of intestinal bacteria by eating fermented food or others.
If you carry out the above 3 things, there is a possibility that osteopontin decreases by the improvement of immune cells.